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1

Pyrazolopyridine inhibitors of B-RafV600E. Part 2: Structure–activity relationships

Steve Wenglowsky, Kateri A. Ahrendt, Alex J. Buckmelter, Bainian Feng, Susan L. Gloor, Stefan Gradl, Jonas Grina, Joshua D. Hansen, Ellen R. Laird, Paul Lunghofer, Simon Mathieu, David Moreno, Brad Ne

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 635 KB

english, 2011

2

Gene Expression Profiling of H9c2 Cells Subjected to H2O2-Induced Apoptosis with/without AF-HF001

Wang, Guping, Tang, Chunlei, Yan, Guijun, Feng, Bainian

Year:

2016

Language:

english

File:

PDF, 1.22 MB

english, 2016

3

Oxadiazole-2-oxides may have other functional targets, in addition to SjTGR, through which they cause mortality in Schistosoma japonicum

Song, Li-Jun, Luo, Huan, Fan, Wen-Hua, Wang, Gu-Ping, Yin, Xu-Ren, Shen, Shuang, Wang, Jie, Jin, Yi, Zhang, Wei, Gao, Hong, Liu, Qian, Wang, Wen-Long, Feng, Bainian, Yu, Chuan-Xin

Journal:

Parasites & Vectors

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

4

Isoliquiritigenin‐induced vasodilation by Activating large‐conductance Ca 2+ ‐activated K + channels In mouse mesenteric arteries

Ye, Yang, Gao, Mengru, Feng, Lei, Feng, Bainian, Ma, Xin

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2019

Language:

english

File:

PDF, 1.16 MB

english, 2019

5

Evaluation of Assay Technologies for the Identification of Protein–Peptide Interaction Antagonists

Kadkhodayan, Saloumeh, Elliott, Linda O., Mausisa, Grace, Wallweber, Heidi Ackerly, Deshayes, Kurt, Feng, Bainian, Fairbrother, Wayne J.

Journal:

Assay and Drug Development Technologies

Year:

2007

Language:

english

File:

PDF, 352 KB

english, 2007

6

Palladium(II)-Catalyzed C–H Acylation with Arylglycine Derivatives

Fan, Weizheng, Su, Jiapeng, Feng, Bainian

Journal:

Year:

2015

Language:

english

File:

PDF, 182 KB

english, 2015

7

A New γ-Glutamyltranspeptidase-Based Intracellular Self-Assembly of Fluorine-18 Labeled Probe for Enhancing PET Imaging in Tumors

Ye, Siqin, Wang, Shijie, Gao, Dingyao, Li, Ke, Liu, Qingzhu, Feng, Bainian, Qiu, Ling, Lin, Jianguo

Journal:

Bioconjugate Chemistry

Year:

2020

Language:

english

File:

PDF, 798 KB

english, 2020

8

ChemInform Abstract: Iron-Catalyzed Direct α-Arylation of α-Amino Carbonyl Compounds with Indoles.

Zhang, Yan, Ni, Minjie, Feng, Bainian

Journal:

Year:

2016

File:

PDF, 29 KB

2016

9

Synthesis and Antiviral Activity of Conformational Analogues of Leucamide A

Wang, Wen-Long, Chen, Hai-Jun, Ma, Wei-Ping, Gu, Min, Fan, Min-Zhi, Li, Jing-Ya, Feng, Bainian, Nan, Fa-Jun

Journal:

Year:

2012

Language:

english

File:

PDF, 299 KB

english, 2012

10

Zebrafish as a New Model for Phenotype-based Screening of Positive Inotropic Agents

Tang, Chunlei, Xie, Desheng, Feng, Bainian

Journal:

Chemical Biology & Drug Design

Year:

2015

Language:

english

File:

PDF, 900 KB

english, 2015

11

Gold-Oxazoline Complex-Catalyzed Cross-Dehydrogenative Coupling of Glycine Derivatives and Alkenes

Ni, Minjie, Zhang, Yan, Gong, Tingting, Feng, Bainian

Journal:

Advanced Synthesis & Catalysis

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

12

Au(iii)-catalyzed intermolecular amidation of benzylic C–H bonds

Zhang, Yan, Feng, Bainian, Zhu, Chengjian

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 172 KB

english, 2012

13

Palladium-Catalyzed Heck-Type Coupling via C–N Cleavage

Fan, Weizheng, Liu, Faming, Feng, Bainian

Journal:

Year:

2015

Language:

english

File:

PDF, 187 KB

english, 2015

14

ChemInform Abstract: Palladium-Catalyzed Heck-Type Coupling via C-N Cleavage.

Fan, Weizheng, Liu, Faming, Feng, Bainian

Journal:

Year:

2015

File:

PDF, 21 KB

2015

15

Pyrazolopyridine Inhibitors of B-RafV600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

Buckmelter, Alex J., Alicke, Bruno, Choo, Edna F., Dinkel, Victoria, Feng, Bainian, Wenglowsky, Steve, Ren, Li, Ahrendt, Kateri A., Laird, Ellen R., Aliagas, Ignacio

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 2.09 MB

english, 2011

16

Immobilizing of oxo-molybdenum complex on cross-linked copolymer and its catalytic activity for epoxidation reactions

Fan, Weizheng, Shi, Dongyang, Feng, Bainian

Journal:

Catalysis Communications

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

17

ChemInform Abstract: An Efficient One-Pot, Three-Component Synthesis of Vinyl Sulfones via Iodide-Catalyzed Radical Alkenylation.

Fan, Weizheng, Su, Jiapeng, Shi, Dongyang, Feng, Bainian

Journal:

Year:

2015

File:

PDF, 20 KB

2015

18

Transition-Metal-Free Trifluoromethylation of Aldehyde-Derivatives with Sodium Trifluoromethanesulfinate

Tan, Zheng, Zhang, Shiwei, Zhang, Yan, Li, Yunpeng, Ni, Minjie, Feng, Bainian

Journal:

Journal of Organic Chemistry

Year:

2017

Language:

english

File:

PDF, 764 KB

english, 2017

19

Determination of an isonicotinohydrazide derivative, a novel positive inotropic compound, in mouse plasma by LC-MS/MS and its application to a pharmacokinetics study

Hui, Renjie, Gao, Yueying, Liu, Jingyi, Liu, Haili, Tang, Chunlei, Feng, Bainian

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2018

Language:

english

File:

PDF, 552 KB

english, 2018

20

Selective Adsorption toward Hg(II) and Inhibitory Effect on Bacterial Growth Occurring on Thiosemicarbazide-Functionalized Chitosan Microsphere Surface

Wang, Yan, Dang, Qi Feng, Liu, Chengsheng, Yu, Dejun, Pu, Xiaoying, Wang, Qiongqiong, Gao, Hong, Zhang, Bainian, Cha, Dongsu

Journal:

ACS Applied Materials & Interfaces

Year:

2018

Language:

english

File:

PDF, 1.83 MB

english, 2018

21

An efficient one-pot, three-component synthesis of vinyl sulfones via iodide-catalyzed radical alkenylation

Fan, Weizheng, Su, Jiapeng, Shi, Dongyang, Feng, Bainian

Journal:

Year:

2015

Language:

english

File:

PDF, 609 KB

english, 2015

22

Total synthesis of rhizoxin D

David R. Williams, Kim M. Werner, Bainian Feng

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 251 KB

english, 1997

23

Synthesis and SAR Studies of Praziquantel Derivatives with Activity against Schistosoma japonicum

Wang, Wen-Long, Song, Li-Jun, Chen, Xia, Yin, Xu-Ren, Fan, Wen-Hua, Wang, Gu-Ping, Yu, Chuan-Xin, Feng, Bainian

Journal:

Year:

2013

Language:

english

File:

PDF, 626 KB

english, 2013

24

Design, synthesis and evaluation of a series of novel phenylpropanoic acid derivatives agonists for the FFA1

Yang, Jiaju, Gu, Enke, Yan, Ting, Shen, Daoming, Feng, Bainian, Tang, Chunlei

Journal:

Chemical Biology & Drug Design

Year:

2019

Language:

english

File:

PDF, 485 KB

english, 2019

25

Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors

Wang, Wen-Long, Huang, Chao, Gao, Li-Xin, Tang, Chun-Lan, Wang, Jun-Qing, Wu, Min-Chen, Sheng, Li, Chen, Hai-Jun, Nan, Fa-Jun, Li, Jing-Ya, Li, Jia, Feng, Bainian

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 4.23 MB

english, 2014

26

ChemInform Abstract: Au(III)-Catalyzed Intermolecular Amidation of Benzylic C-H Bonds.

Zhang, Yan, Feng, Bainian, Zhu, Chengjian

Journal:

Year:

2013

File:

PDF, 29 KB

2013

27

Synthesis of Novel 3-aryl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene Derivatives and Their Biological Evaluation Against Protein Tyrosine Phosphatase 1B

Wang, Wen-Long, Chen, Xia, Gao, Li-Xin, Sheng, Li, Li, Jing-Ya, Li, Jia, Feng, Bainian

Journal:

Chemical Biology & Drug Design

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

28

Synthesis and SAR of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as potent and selective CDK4/6 inhibitors

Zhao, Hui, Hu, Xiaoxia, Cao, Kai, Zhang, Yue, Zhao, Kuantao, Tang, Chunlei, Feng, Bainian

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 645 KB

english, 2018

29

Gold-Catalyzed Direct Indolation of Tetrahydroisoquinolines

Zhang, Yan, Luo, Sha, Feng, Bainian, Zhu, Chengjian

Journal:

Chinese Journal of Chemistry

Year:

2012

Language:

english

File:

PDF, 361 KB

english, 2012

30

Rh(I)-catalyzed decarbonylation synthesis of carbazoles via C–N cleavage

Fan, Weizheng, Jiang, Shan, Feng, Bainian

Journal:

Year:

2015

Language:

english

File:

PDF, 437 KB

english, 2015

31

Interleukin 10 protects primary melanocyte by activation of Stat-3 and PI3K/Akt/NF-κB signaling pathways

Zhou, Jia, Ling, Jingjing, Song, Jing, Wang, Yong, Feng, Bainian, Ping, Fengfeng

Journal:

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

32

ChemInform Abstract: TBAI-Catalyzed Synthesis of α-Ketoamides via sp 3 C-H Radical/Radical Cross-Coupling and Domino Aerobic Oxidation.

Fan, Weizheng, Shi, Dongyang, Feng, Bainian

Journal:

Year:

2015

File:

PDF, 94 KB

2015

33

Design, synthesis and biological evaluation of 2-(4-(methylsulfonyl)phenyl)pyridine derivatives as GPR119 agonists

Zhou, Ying, Zhu, Xiaoyun, Zhang, Leilei, Tang, Chunlei, Feng, Bainian

Journal:

Chemical Biology & Drug Design

Year:

2018

Language:

english

File:

PDF, 715 KB

english, 2018

34

ChemInform Abstract: Palladium(II)-Catalyzed C-H Acylation with Arylglycine Derivatives.

Fan, Weizheng, Su, Jiapeng, Feng, Bainian

Journal:

Year:

2015

File:

PDF, 21 KB

2015

35

TBAI-catalyzed synthesis of α-ketoamides via sp3 C–H radical/radical cross-coupling and domino aerobic oxidation

Fan, Weizheng, Shi, Dongyang, Feng, Bainian

Journal:

Tetrahedron Letters

Year:

2015

Language:

english

File:

PDF, 662 KB

english, 2015

36

ChemInform Abstract: Rh(I)-Catalyzed Decarbonylation Synthesis of Carbazoles via C-N Cleavage.

Fan, Weizheng, Jiang, Shan, Feng, Bainian

Journal:

Year:

2015

File:

PDF, 21 KB

2015

37

Iron-catalyzed direct a-arylation of a-amino carbonyl compounds with indoles

Zhang, Yan, Ni, Minjie, Feng, Bainian

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 747 KB

english, 2015

38

Synthesis and biological evaluation of novel 5,6-dihydropyrimido[4,5-f]quinazoline derivatives as potent CDK2 inhibitors

Hu, Xiaoxia, Zhao, Hui, Wang, Youzhi, Liu, Zhan, Feng, Bainian, Tang, Chunlei

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 757 KB

english, 2018

39

Discovery and biological evaluation of novel G protein-coupled receptor 119 agonists for type 2 diabetes

Zhou, Ying, Wang, Youzhi, Zhang, Leilei, Tang, Chunlei, Feng, Bainian

Journal:

Archiv der Pharmazie

Year:

2019

Language:

english

File:

PDF, 871 KB

english, 2019

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